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The complete oxidation of one glucose molecule via aerobic respiration yields a much higher net ATP than fermentation mainly because:

  • A Aerobic respiration fully oxidizes glucose to CO2 and water, extracting far more energy via the electron transport chain
  • B Aerobic respiration skips glycolysis largely, conserving more energy in typical laboratory settings under usual circumstances
  • C Fermentation occurs mainly in the mitochondrial matrix, limiting enzyme access under normal conditions as generally observed
  • D Fermentation produces additional CO2 that aerobic respiration does not release as frequently documented in most reference accounts

Correct answer: A. Aerobic respiration fully oxidizes glucose to CO2 and water, extracting far more energy via the electron transport chain

Explanation: Aerobic respiration completely oxidizes glucose to CO2 and H2O, with most ATP generated through the electron transport chain, whereas fermentation only partially oxidizes glucose, yielding far less ATP.

Concept context

Glycolysis, the Krebs cycle, the electron transport chain, fermentation, and the respiratory quotient. The cellular energy-release counterpart to photosynthesis.

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