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Explain the sliding filament theory of muscle contraction.

  • A Muscle contracts by folding the thin actin filaments into tightly compacted coils along the sarcomere structure as generally observed in typical laboratory settings
  • B Thin actin filaments slide over thick myosin filaments using cross-bridge cycling powered by ATP; the sarcomere shortens while filament lengths stay constant
  • C Myosin filaments physically shorten in their overall structural length during the course of muscle contraction itself under usual circumstances according to most researchers
  • D Both the thin actin and thick myosin filaments shorten together by a roughly equal amount during contraction in the majority of cases studied as widely reported

Correct answer: B. Thin actin filaments slide over thick myosin filaments using cross-bridge cycling powered by ATP; the sarcomere shortens while filament lengths stay constant

Explanation: Sliding filament theory (Huxley, 1954): myosin heads form cross-bridges with actin; using ATP hydrolysis, heads pivot (power stroke) pulling actin toward center; new ATP allows detachment; heads reset and cycle repeats. Result: actin slides over myosin, Z discs come closer, sarcomere shortens, muscle contracts.

Concept context

Types of movement, muscle contraction, skeletal system, joints, and disorders. Important for Class 11 and NEET.

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