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What is the role of oxytocin in parturition and breastfeeding?

  • A Oxytocin mainly regulates water balance through its action on the kidney collecting ducts as frequently described in most textbook accounts
  • B Oxytocin causes uterine contractions during labor (positive feedback loop) and milk ejection (let-down reflex) during breastfeeding
  • C Oxytocin is sometimes mistakenly thought to suppress uterine contractions throughout the process of labor during normal conditions
  • D Oxytocin directly synthesizes milk proteins within the mammary alveolar cells, according to some misconceptions as generally observed

Correct answer: B. Oxytocin causes uterine contractions during labor (positive feedback loop) and milk ejection (let-down reflex) during breastfeeding

Explanation: Oxytocin (from posterior pituitary): triggers uterine contractions during labor in a positive feedback loop (contractions stimulate more oxytocin release). During breastfeeding, infant suckling triggers oxytocin release causing milk ejection (let-down reflex). Synthetic oxytocin (Pitocin) is used to induce labor.

Concept context

Male and female reproductive systems, gametogenesis, fertilization, implantation, pregnancy, and reproductive health.

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