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Difference Between Innate Immunity and Acquired Immunity

The body defends itself with two lines of immunity - one you are born with and one you develop over time.

In short

Innate (non-specific) immunity is present from birth and responds the same way to all pathogens without memory; acquired (specific) immunity develops after exposure, is pathogen-specific and has memory.

Innate Immunity vs Acquired Immunity - Comparison Table

BasisInnate ImmunityAcquired Immunity
Present fromBirth (inborn)Develops after exposure
SpecificityNon-specificPathogen-specific
MemoryNo memoryHas memory cells
Response speedImmediateSlower (first exposure)
ComponentsSkin, phagocytes, inflammationB-cells and T-cells (antibodies)

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Frequently Asked Questions - Innate Immunity vs Acquired Immunity

What are the two types of acquired immunity?
Acquired immunity is of two types: humoral (antibody-mediated) immunity carried out by B-lymphocytes, and cell-mediated immunity carried out by T-lymphocytes.
Is a vaccine innate or acquired immunity?
A vaccine produces acquired immunity - it exposes the body to a harmless form of the antigen so memory cells form and give a fast, specific response on later infection.