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Difference Between DNA and RNA

DNA and RNA are the two nucleic acids that store and transfer genetic information. They differ in sugar, bases, structure, and function.

In short

DNA is a double-stranded molecule with deoxyribose sugar and the base thymine that stores genetic information; RNA is usually single-stranded with ribose sugar and the base uracil, and carries out protein synthesis.

DNA vs RNA — Comparison Table

BasisDNARNA
Full formDeoxyribonucleic acidRibonucleic acid
SugarDeoxyriboseRibose
StrandsDouble-stranded (usually)Single-stranded (usually)
Nitrogen basesA, T, G, CA, U, G, C
Unique baseThymine (T)Uracil (U)
FunctionStores genetic informationTransfers info, protein synthesis
StabilityMore stableLess stable

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Frequently Asked Questions — DNA vs RNA

Why is DNA more stable than RNA?
DNA lacks the reactive 2ʹ-OH group present in RNA (it has deoxyribose), and its double-stranded structure protects it — making DNA better suited for long-term storage of genetic information.
Which base is found in RNA but not DNA?
Uracil (U) is found in RNA instead of thymine (T), which is present in DNA.