- A Voltage-gated Na+ channels that are mainly responsible for the rising phase of the action potential itself under typical conditions
- B Scaffold proteins (PSD-95), AMPA and NMDA receptors, signaling enzymes (CaMKII) -- organizing the postsynaptic signaling complex
- C Mainly nicotinic acetylcholine receptors, with very few glutamate receptors present overall according to standard textbooks
- D Mainly inhibitory GABA-A receptors that are clustered tightly at the postsynaptic membrane surface region in general practice
Correct answer: B. Scaffold proteins (PSD-95), AMPA and NMDA receptors, signaling enzymes (CaMKII) -- organizing the postsynaptic signaling complex
Explanation: PSD: electron-dense specialization at excitatory synapses. PSD-95 (scaffold protein) anchors NMDA receptors; recruits AMPA receptors, CaMKII, nNOS, and other signaling proteins.
Concept context
Brain, spinal cord, neurons, reflex arcs, and sense organs.