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The Hodgkin-Huxley model of the action potential uses which equation?

  • A Mainly a simple, fixed-threshold equation that includes few voltage-dependent gating variables present in general practice
  • B Differential equations with m, h (Na+ channel gating) and n (K+ channel gating) variables derived from voltage-clamp experiments
  • C Ohm's law alone, relating membrane current directly to voltage and a fixed resistance term value as frequently described in most textbook accounts
  • D The Nernst equation alone, describing mainly the equilibrium potential of a single permeant ion species during normal conditions

Correct answer: B. Differential equations with m, h (Na+ channel gating) and n (K+ channel gating) variables derived from voltage-clamp experiments

Explanation: Hodgkin-Huxley model (1952 Nobel Prize): conductance-based equations using m^3h (Na+ activation/inactivation) and n^4 (K+ activation) variables, accurately reproducing action potential shape and propagation.

Concept context

Brain, spinal cord, neurons, reflex arcs, and sense organs.

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