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Which experiment provided direct evidence for semiconservative DNA replication?

  • A Griffith's transformation experiment
  • B Hershey-Chase experiment
  • C Meselson-Stahl experiment
  • D Avery-MacLeod-McCarty experiment

Correct answer: C. Meselson-Stahl experiment

Explanation: Meselson and Stahl used 15N and 14N labelled E. coli DNA and density gradient centrifugation to confirm semiconservative replication.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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