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Which enzyme unwinds the DNA double helix at the replication fork?

  • A DNA polymerase
  • B Helicase
  • C Ligase
  • D Primase

Correct answer: B. Helicase

Explanation: Helicase unwinds the parental DNA double helix at the replication fork, separating the two strands for replication.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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