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The wobble hypothesis explains how:

  • A How ribosomes physically move stepwise along the mRNA strand
  • B A single tRNA can recognise more than one codon for the same amino acid
  • C How RNA polymerase correctly selects the appropriate gene promoter
  • D How spliceosomes remove introns from precursor hnRNA transcripts

Correct answer: B. A single tRNA can recognise more than one codon for the same amino acid

Explanation: The wobble hypothesis states that the pairing at the third codon position can be flexible, letting one tRNA recognise multiple synonymous codons.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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