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On the lagging strand, DNA synthesis proceeds:

  • A Continuously in the same direction as the replication fork movement
  • B Discontinuously, away from the replication fork, in short fragments
  • C Without any RNA primer
  • D In the 3 prime to 5 prime direction by DNA polymerase

Correct answer: B. Discontinuously, away from the replication fork, in short fragments

Explanation: Because DNA polymerase synthesises only 5 prime to 3 prime, the lagging strand is made discontinuously in short Okazaki fragments moving away from the fork.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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