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What is the function of the signal recognition particle (SRP)?

  • A Initiates unwinding of the DNA double helix at the origin of replication
  • B Directs ribosome-mRNA complex to rough ER
  • C Enzymatically cleaves the signal peptide once translocation is complete
  • D Catalyzes correct folding of nascent polypeptides within the ER lumen

Correct answer: B. Directs ribosome-mRNA complex to rough ER

Explanation: SRP recognizes the signal sequence on a growing polypeptide and targets the ribosome-mRNA complex to the rough ER membrane.

Concept context

Cell theory, prokaryotic vs eukaryotic cells, organelles and their functions. Foundation of all biology.

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