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🔬 Biology  ·  Principles of Inheritance and Variation  ·  NEET

The locus control region (LCR) regulates:

  • A Mainly the localized pattern of DNA methylation occurring across a single gene cluster
  • B Long-range transcriptional regulation of gene clusters (e.g., globin gene cluster)
  • C Mainly the removal of introns from pre-mRNA carried out by the spliceosome complex
  • D Mainly the recruitment of ribosomes needed to begin translation of a mature mRNA

Correct answer: B. Long-range transcriptional regulation of gene clusters (e.g., globin gene cluster)

Explanation: LCR: regulatory element that controls chromatin accessibility and transcription of entire gene clusters over long distances (10s of kb). e.g., beta-globin LCR.

Concept context

Mendel's laws, inheritance patterns, DNA structure, and molecular biology. Core of NEET biology.

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