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🔬 Biology  ·  Principles of Inheritance and Variation  ·  NEET

CpG islands in the genome are:

  • A Genomic repetitive sequences that occur scattered randomly throughout most intronic regions of the genome in standard practice
  • B Regions with high C-G dinucleotide frequency, usually unmethylated near gene promoters; hypermethylation silences genes in cancer
  • C Sequences found mainly packed within densely compacted, transcriptionally silent heterochromatin regions under most conditions encountered
  • D Regions of the genome characterized by an unusually elevated rate of meiotic recombination events as frequently observed in practice

Correct answer: B. Regions with high C-G dinucleotide frequency, usually unmethylated near gene promoters; hypermethylation silences genes in cancer

Explanation: CpG islands: regions rich in CpG dinucleotides at gene promoters. Normally unmethylated (active genes). Hypermethylation silences tumor suppressor genes in cancer.

Concept context

Mendel's laws, inheritance patterns, DNA structure, and molecular biology. Core of NEET biology.

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