- A Improved diagnostic technology that detects disease earlier in a person's life according to most researchers
- B Trinucleotide repeat expansion through generations causing more severe disease at earlier onset
- C Switching of parental imprinting marks occurring between successive generations in the majority of cases studied
- D Translocation of a chromosome segment onto an unrelated non-homologous chromosome as widely reported
Correct answer: B. Trinucleotide repeat expansion through generations causing more severe disease at earlier onset
Explanation: Anticipation: disease onset earlier and more severe in successive generations. Caused by unstable trinucleotide repeat expansions (longer repeats = more severe). E.g., Huntington disease, myotonic dystrophy.
Concept context
Mendel's laws, inheritance patterns, DNA structure, and molecular biology. Core of NEET biology.
Read the full Principles of Inheritance and Variation notes →