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What causes the symptoms of inflammation (redness, swelling, heat, pain)?

  • A Direct mechanical damage inflicted on tissue by the invading pathogen itself over time
  • B Release of histamine and other chemicals that increase blood flow and vascular permeability
  • C Activation of cytotoxic T cells that are circulating near the wound site
  • D Formation of new antibodies by plasma cells residing within nearby lymph nodes

Correct answer: B. Release of histamine and other chemicals that increase blood flow and vascular permeability

Explanation: Inflammation is triggered by damaged cells releasing histamine, prostaglandins, and cytokines. These cause vasodilation (increased blood flow = redness, heat) and increased vascular permeability (fluid leaks = swelling), also activating pain receptors.

Concept context

Innate and adaptive immunity, B cells, T cells, antibodies, vaccines, and immune disorders. Critical for NEET.

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