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What are cytokines and give examples?

  • A A specific type of antibody secreted mainly by activated plasma cells residing within lymph nodes under usual circumstances according to most researchers
  • B Signaling proteins that regulate immune cell communication and function: interleukins (IL-1, IL-2, IL-4), interferons, TNF, chemokines
  • C Complement proteins that circulate freely and become activated by antigen-antibody complex formation over time in the majority of cases studied
  • D Enzymes secreted by phagocytes that chemically digest engulfed antigens inside lysosomal compartments over time as widely reported

Correct answer: B. Signaling proteins that regulate immune cell communication and function: interleukins (IL-1, IL-2, IL-4), interferons, TNF, chemokines

Explanation: Cytokines are small signaling proteins that mediate cell-to-cell communication in immunity. Interleukins (IL-2 stimulates T cell proliferation; IL-4 promotes B cell differentiation to IgE). Interferons (antiviral), TNF-alpha (inflammation), chemokines (direct cell migration).

Concept context

Innate and adaptive immunity, B cells, T cells, antibodies, vaccines, and immune disorders. Critical for NEET.

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