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What are autoimmune diseases? Give two examples.

  • A Diseases caused entirely by invading external bacterial or viral pathogens from outside the body
  • B Diseases where the immune system attacks the body's own tissues
  • C Genetic diseases that are inherited directly from one or both biological parents
  • D Diseases resulting from a congenital deficiency in the total number of immune cells

Correct answer: B. Diseases where the immune system attacks the body's own tissues

Explanation: Autoimmune diseases occur when self-tolerance breaks down and the immune system attacks self-antigens. Examples: Type 1 diabetes (attack on pancreatic beta cells), Rheumatoid arthritis (attack on joint synovium), Systemic lupus erythematosus (anti-nuclear antibodies), Multiple sclerosis (attack on myelin).

Concept context

Innate and adaptive immunity, B cells, T cells, antibodies, vaccines, and immune disorders. Critical for NEET.

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