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What is the basic principle of antibiotic therapy?

  • A Antibiotics act mainly by directly destroying viral capsids and degrading viral genetic material inside infected host cells as frequently observed in practice
  • B Antibiotics target structures unique to bacteria (cell wall, ribosomes) that are absent in human cells, killing bacteria without harming the host
  • C Antibiotics work mainly by generally strengthening the host's own innate and adaptive cellular immune defenses over time in many documented cases
  • D Antibiotics are considered equally effective treatments against most bacterial, viral, and fungal infections alike according to conventional understanding

Correct answer: B. Antibiotics target structures unique to bacteria (cell wall, ribosomes) that are absent in human cells, killing bacteria without harming the host

Explanation: Antibiotics exploit differences between bacterial and human cells: beta-lactams (penicillin) target bacterial cell wall (peptidoglycan); tetracyclines target bacterial 70S ribosomes; fluoroquinolones target bacterial DNA gyrase. These targets are absent or different in human cells, providing selective toxicity.

Concept context

Pathogens, infectious diseases, non-infectious diseases, drugs, cancer, and public health. High NEET importance.

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