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Negative feedback in the endocrine system means:

  • A Rising hormone levels sometimes trigger the hypothalamus to release more releasing factors
  • B Increased hormone levels signal the gland to reduce further production (maintaining balance)
  • C Target tissues sometimes amplify the hormonal signal through second messenger cascades
  • D Antagonistic glands typically secrete in roughly equal proportions most of the time

Correct answer: B. Increased hormone levels signal the gland to reduce further production (maintaining balance)

Explanation: Negative feedback: high levels of a hormone inhibit further secretion. E.g., high cortisol inhibits ACTH and CRH. Maintains homeostasis.

Concept context

The endocrine glands, hormone classification and mechanism of action, and negative feedback regulation.

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