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🔬 Biology  ·  Chemical Coordination and Integration  ·  NEET

In Addison's disease, hyposecretion of adrenal cortex hormones leads to all of the following except:

  • A Increased skin pigmentation linked to elevated ACTH
  • B Weakness and fatigue from impaired glucose mobilization
  • C Low blood sodium from reduced aldosterone activity
  • D Increased blood pressure due to sodium retention

Correct answer: D. Increased blood pressure due to sodium retention

Explanation: Addison's disease lowers aldosterone and cortisol, causing sodium loss, hypotension (not increased blood pressure), fatigue, and hyperpigmentation from compensatory ACTH rise.

Concept context

The endocrine glands, hormone classification and mechanism of action, and negative feedback regulation.

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