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🔬 Biology  ·  Cell Cycle and Cell Division  ·  NEET

The Holliday junction in recombination is:

  • A A specific site along the chromosome where double-strand breaks occur before any strand invasion or branch migration ever takes place there
  • B A four-way DNA junction formed during crossing-over (resolved to form crossover or non-crossover products)
  • C A multi-subunit protein complex that mediates chromosome cohesion composed of cohesin subunits rather than any recombining DNA strands
  • D A chromatin modification that marks regions destined for recombination deposited well before meiosis begins, unrelated to active strand exchange

Correct answer: B. A four-way DNA junction formed during crossing-over (resolved to form crossover or non-crossover products)

Explanation: Holliday junction: four-stranded structure formed by branch migration during recombination. Resolution by resolvases determines if crossover (CO) or non-crossover (NCO) outcome.

Concept context

Mitosis and meiosis: how cells divide for growth, repair, and reproduction.

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