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Recombinant DNA is made by:

  • A Randomly mutating existing DNA using chemical mutagens
  • B Cutting DNA with restriction enzymes and joining foreign DNA with ligase
  • C Copying DNA exclusively through repeated PCR amplification cycles
  • D Physically excising genes from chromosomes without replacement

Correct answer: B. Cutting DNA with restriction enzymes and joining foreign DNA with ligase

Explanation: Recombinant DNA: restriction enzymes cut host and foreign DNA; ligase joins them. The resulting hybrid DNA molecule is recombinant DNA.

Concept context

Recombinant DNA, GMOs, PCR, CRISPR, and biotechnology applications. Growing importance in NEET.

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