- A Sequencing the very first complete bacterial genome using classical Sanger sequencing chemistry methods in general practice
- B Solving the protein folding problem by accurately predicting 3D protein structure from amino acid sequence using deep learning
- C Performing the first successful gene editing experiment ever carried out using CRISPR-Cas9 technology as frequently described
- D Producing the very first monoclonal antibody using classical hybridoma fusion technology methods in most textbook accounts
Correct answer: B. Solving the protein folding problem by accurately predicting 3D protein structure from amino acid sequence using deep learning
Explanation: AlphaFold (2020): AI system that predicted protein 3D structure from sequence with near-experimental accuracy. Solved the 50-year protein folding problem. Now provides structures for most known proteins.
Concept context
Recombinant DNA, GMOs, PCR, CRISPR, and biotechnology applications. Growing importance in NEET.
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