- A Simple single-cell cultures that are grown as a flat monolayer spread evenly across a culture dish surface area under most conditions encountered
- B 3D mini-organs self-organized from stem cells that recapitulate tissue architecture and function (used for disease modeling and drug testing)
- C Thin tissue slices that are cut directly from a freshly removed surgical organ specimen in the operating room itself as frequently observed in practice
- D Structures that are reported to mainly be grown and studied within the body of a living animal host generally in many documented cases according to conventional understanding
Correct answer: B. 3D mini-organs self-organized from stem cells that recapitulate tissue architecture and function (used for disease modeling and drug testing)
Explanation: Organoids: 3D self-organizing structures grown from stem cells or adult tissue stem cells in extracellular matrix. Recapitulate tissue structure/function. Used for disease models, drug screens, personalized medicine.
Concept context
GM crops, transgenic animals, gene therapy, molecular diagnostics, and bioethics. Frequent 2–3 mark questions in NEET.