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The Michaelis constant (Km) of an enzyme represents

  • A The maximum reaction rate achieved when the enzyme is fully saturated
  • B Substrate concentration at half Vmax
  • C The total enzyme concentration present within the reaction mixture
  • D The pH value at which the enzyme shows peak catalytic activity

Correct answer: B. Substrate concentration at half Vmax

Explanation: Km is the substrate concentration at which the reaction velocity is half of Vmax. A lower Km means higher affinity of enzyme for substrate.

Concept context

Carbohydrates, proteins, lipids, nucleic acids, and enzyme kinetics. Essential foundation for understanding metabolism.

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