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The Bohr effect explains why hemoglobin releases O2 in metabolically active tissues. Which factors cause this?

  • A High O2 and low CO2
  • B Low CO2 and high pH
  • C High CO2 and low pH
  • D High pH and low temperature

Correct answer: C. High CO2 and low pH

Explanation: The Bohr effect: high CO2 (lowers pH by forming carbonic acid) and high H+ decrease hemoglobin affinity for O2. This promotes O2 release in active tissues where CO2 is produced.

Concept context

Carbohydrates, proteins, lipids, nucleic acids, and enzyme kinetics. Essential foundation for understanding metabolism.

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